APPLICATION OF TARGETED HIGH-THROUGHPUT SEQUENCING AS A DIAGNOSTIC TOOL FOR NEONATAL GENETIC METABOLIC DISEASES FOLLOWING TANDEM MASS SPECTROMETRY SCREENING

BackgroundTandem mass spectrometry (MS/MS) is a crucial technique for detecting inborn errors of metabolism (IEM) in newborns.However, the high false positive rate poses challenges in diagnosing specific types of diseases.Therefore, this study aimed to evaluate the role buy shredder ptc of targeted next-generation sequencing (NGS) in the accurate d

When the end leakage flux or q60 headers end leakage inductance cannot be ignored in a permanent magnet (PM) machine (e.g., a PM machine with a short axial length), the analysis of the machine is a time-consuming three-dimensional (3-D) issue.Existing research has made the end leakage inductance no longer to hinder that the performance calculation

The objective of this research was to evaluate the stress corrosion cracking (SCC) of X-70 micro-alloyed steel in contact with bio-ethanol and E-50 gasohol.Environmental factors, including water (1%, 3% and 5%) rivolis las vegas and NaCl (10 mg/L and 32 mg/L), as well as two aging treatments were studied.Experimental values were obtained by the Slo

The shipbuilding design rules require several criteria for the assessment of any floating structure.For this technical paper, a 23000 accles and shelvoke t off-shore barge is assessed by oblique waves global strength criteria.Two barge concepts are evaluated, with the main changes of breadth and draught.Focusing on the preliminary analysis that inv

Since several years, the overall awareness for the necessity to consider a vehicle as a potentially vulnerable system is facing accelerated growth.In 2015, the safety relevant exploitability of vulnerabilities through cyber 2009 buick lucerne catalytic converter attacks was exposed to a broader public for the first time.Only a few months after this